Research Scientist

Company: Tempus
Location: Chicago
Posted on: November 18, 2024

Job Description:

Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are looking for a highly skilledResearch Scientistto join our Biological Modeling team to support Organoid Based Screening. Our CAP accredited facility develops human tumor models for use in a range of studies with our academic and commercial partners to discover next-generation cancer therapies. The ideal candidate will have a strong understanding of molecular gene editing, fluorescent imaging, image analysis, protein detection, and cell culture techniques. Post-doctoral and/or industry experience employing human organoid tissue models in high-throughput formats is preferred.
The successful candidate must be able to work in a fast-paced multidisciplinary environment and will be expected to communicate results both internally and to commercial partners.
What You'll Do:

• 
  
• Work in a collaborative, interdisciplinary team of scientists employing gene-editing approaches to perturb cellular pathways with the aim of identifying therapeutic targets
  
• Design and execute high-throughput gene-editing, imaging, and protein detection workflows
  
• Culture primary human tissue samples
  
• Work with automated liquid and plate platforms at all stages of development
  
• Execute sequencing studies end-to-end
  
• Develop analysis pipelines to process and visualize large high-throughput data sets
  
• Generate summary reports of screening results and molecular data for customer deliverables
  
  Qualifications:
  
  • 
    
  • Ph.D. in oncology, molecular systems biology, or a related field
    
  • 1+ years of industry or post-doctoral experience
    
  • Experience with 3D tissue models preferred, general cell culture experience is a must
    
  • Experience generating and assessing next-generation sequencing data is preferred
    
  • Proficiency in R and/or Python strongly preferred
    
  • Experience with brightfield and fluorescent microscopy
    
  • Experience coordinating complex experimental workflows across multidisciplinary teams
    
  • Previous experience developing methods for and/or operating automated liquid handlers (Biomek, Echo, etc.)
    
    Benefits:
    
    • 
      
    • Competitive salary and benefits package
      
    • Collaborative and supportive work environment
      
    • Chance to make a real impact on the healthcare industry
      
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Keywords: Tempus, Cicero , Research Scientist, Other , Chicago, Illinois